The Delphic sibyl foretold the coming of a great prophet who would be born to a virgin who knew nothing of the corruption of man. A wind is blowing over the prophetess; her hair trails out behind her two genii that stand behind her mimicking her actions, also seems ruffled by this wind. This sense of the blowing wind together with sibyl's wide-eyed and fearful expression, with her mouth ajar as she looks out past the viewer to see the future that approaches, gives the "Delphic Sibyl" a grave air of import.
Like the "Cumaean Sibyl," the "Delphic Sibyl" is placed in a frontal position, while the other sibyls are all seen in varying degrees of a twisted, half-turned position. The "Delphic Sibyl" is a delicate, feminine features and a well-proportioned body.
Michelangelo used startling colors in the robes of the "Delphic Sibyl" creating a vivid contrast of burnt orange and lime green.