This 15 chapter movie serial marked Elmo Lincoln's return to the part of Tarzan, whom he was the first to play, but it was also Lincoln's last time as the character. The serial was advertised as "Censor-proof." Nevertheless, censorship forced the previously bare-chested Lincoln to cover up and wear an over-the-shoulder-styled costume for this production.
Jane was played by Louise Lorraine, who celebrated her sixteenth birthday during production.
The serial is partially based on the novels "The Return of Tarzan" and "Tarzan and the Jewels of Opar" by Edgar Rice Burroughs. The serial's prologue featured Edgar Rice Burroughs himself.