Tarzan is called to Brazil by an old friend to help stop the Jaguar Cult, led by Barcuma, from running off Dr. Ann Philips who is there to give much-needed innoculations to native villagers along the Amazon River. Tarzan is assisted by Baron, a lion, and Cheeta, a chimpanzee (both of whom he brought from Africa), and Captain Sam Bishop, a riverboat pilot, and his young ward, Pepe. The movie was filmed entirely on location in Brazil and along the Amazon River. Dinky, the chimp portraying Cheeta, bit Mike Henry on the jaw during filming, requiring twenty stitches. The chimpanzee was destroyed, and Henry later sued the producers for this accident and other unsafe working conditions on all three of his Tarzan films. The parties settled out of court.